微波辐射微流体法制备LaPO4: Eu3+纳米发光颗粒与结晶过程控制

he lanthanide-doped fluorescent nanocrystals (NCs) show great potential in applications at research fields of immunobiology and clinical examination for this kind of NCs have low-toxicity, wide Stokes-shift, high resistance to the photobleaching, emission-twinkling and photodegradation. However, the lanthanide- doped NCs produced by the conventional methods usually have wide size distribution, large diameter, poor dispersibility and low emission yield. They could hardly meet the requirements of bio-labeling, which need excellent redispersibility, well water-solubility, and strong emission intensity. In this paper, LaPO4: Eu3+ fluorescent NCs were prepared by microfluidic reactor by microwave irradiation in aqueous phase. The nucleation and growth processes were analyzed by the microspace by microfluidic reactor combined with microwave irradiation. The redispersibility, water-solubility and the fluorescent intensity were enhanced by optimizing the process in microreactor.