三七虫草混合粉抑制小鼠黑色素瘤效应研究

Objective To explore the anti-tumor effect of the powder of Panax notoginseng and Cordyceps sinensis （SCF） and its effect on immune organs through in vivo experiment on the basis of B16 transplanted tumor model. Methods Found B16 transplanted tumor modal which were divided into 6 groups. From the second day of inoculation， all mice were administrate respectively once a day for 10 days， except CTX group injected intravenously once in another day for 3 times. Until 15th day， mice were sacrificed to assay inhibitory rate of tumor， mass of immune organs and ordinal conditions. Results All mice entered the final analysis without loss. All different dosage SCF groups could inhibit the growth of B16 tumor in mice and inhibitory rate were 48％， 42％， 36.4％ respectively， there are significant difference from control group. Meanwhile， it could also protect indexes of thymus and spleen of tumor mice， and there are no obvious side effects. Conclusion： SCF has an remarkable effect on inhibiting proliferation of tumor， it also can improve survival condition efficiently， probably protect and restore immune organs.