釉原蛋白在牙釉质仿生矿化中的研究进展

Enamel is the hardest tissue in human body, it is composed by a highly ordered arrangement of hydroxyapatite, such arrangement with excellent mechanical properties was by regulated by a series of enamel matrix protein. Among which, amelogenin, which composes more than 90% of enamel organic ingredients, plays an important role in the formation of enamel. This paper will review research progress of the role of amelogenin in enamel development, in vitro self-assembly of amelogenin and it's effect on the regulation of inorganic ions crystallization, as well as amelogenin biomimetic mineralization.)