石墨烯/生物玻璃复合支架材料的制备

Graphene oxide (GO) has been widely used as a biomaterial for various biomedical applications. However, it remains challenging to functionalize GO as ideal biological scaffold. Herein, we report facile functionalization of GO with dopamine and subsequent bioactive glass (BG) to enhance its bioactivity. On the basis of graphene, we obtained dopamine functionalized graphene oxide/bioactive glass (DGO/BG) hybrid scaffolds containing different content of DGO by loading BG nanoparticles on graphene oxide surface using sol-gel method. To enhance the dispersion stability and facilitate subsequent nucleation of BG in GO, firstly, dopamine (DA) was used to modify GO. Then, the modified GO was functionalized with bioactive glass (BG) using sol-gelmethod. The as achieved DGO/BG hybrid scaffolds have great potential or elicit desired bone reparative outcome.