对药物疗效问题的研究
rug efficacy study
药-时曲线反映了一种药物的浓度在人体内随时间的变化,是医生给药的依据,也是检验药品的重要指标,本文对这个问题进行了深入的探讨。我们首先据药物动力学理论建立了描述药-时曲线的房室模型,接着,从纯粹数学理论出发建立了非线性回归模型。我们发现这两种模型的结果不尽然相同,对这两个模型进行的具体分析发现两个模型各有优缺点,然后,我们将两者结合得到了一个能够很好地描述药物浓度随时间变化的模型。
medicine - when the curve reflects a concentration of the drug in the human body changes with time, a doctor on the basis of the administration, drug testing is an important indicator of this article the issue in detail. It was our first pharmacokinetic theory to describe the drug - when the curve of the compartment model, and then, from a purely mathematical theory to build a non-linear regression model. We found that the results of these two models are not necessarily the same, these two models for specific analysis of the two models have their own strengths and weaknesses, and then we will be a combination of both a very good description of drug concentrations over time Model.
石玉文、梁翥、周柳阳
药学数学基础医学
药-时曲线房室模型非线性回归
drugs – time linearsCompartment modelNon-linear regression
石玉文,梁翥,周柳阳.对药物疗效问题的研究[EB/OL].(2008-12-02)[2025-08-16].http://www.paper.edu.cn/releasepaper/content/200812-66.点此复制
评论