Which traits predict elevated distress during the Covid-19 pandemic? Results from a large, longitudinal cohort study with psychiatric patients and healthy controls
Which traits predict elevated distress during the Covid-19 pandemic? Results from a large, longitudinal cohort study with psychiatric patients and healthy controls
Abstract BackgroundThe Covid-19 pandemic resulted in repeated, prolonged restrictions in daily life. Social distancing policies as well as health anxiety are thought to lead to mental health impairment. However, there is lack of longitudinal data identifying at-risk populations particularly vulnerable for elevated Covid-19-related distress. MethodsWe collected data of N=1268 participants (n=622 healthy controls (HC), and n=646 patients with major depression, bipolar disorder, schizophrenia or schizoaffective disorder) at baseline (2014-2018) and during the first lockdown in Germany (April-May 2020). We obtained information on Covid-19 restrictions (number and subjective impact of Covid-19 events), and Covid-19-related distress (i.e., subjective fear and isolation). Using multiple linear regression models including trait variables and individual Covid-19 impact, we sought to predict Covid-19-related distress. ResultsHC and patients reported similar numbers of Covid-19-related events, and similar subjective impact rating. They did not differ in Covid-19-related subjective fear. Patients reported significantly higher subjective isolation. 30.5% of patients reported worsened self-rated symptoms since the pandemic. Subjective fear in all participants was predicted by four variables: trait anxiety (STAI-T), conscientiousness (NEO-FFI), Covid-19 impact, and sex. Subjective isolation in HC was predicted by social support (FSozu), Covid-19 impact, age, and sex; in patients, it was predicted by social support and Covid-19 impact. ConclusionOur data shed light on differential effects of the pandemic in psychiatric patients and HC. They identify relevant, easy-to-obtain variables for risk profiles related to interindividual differences in Covid-19-related distress for direct translation into clinical practice.
Waltemate Lena、Meller Tina、Schmitt Simon、Meinert Susanne、Dohm Katharina、Dannlowski Udo、Pfarr Julia-Katharina、Nenadi? Igor、Kircher Tilo、Leehr Elisabeth J.、Stein Frederike、Thiel Katharina、Krug Axel、Ringwald Kai G.、Brosch Katharina、H¨1lsmann Carina、Lemke Hannah、Schrammen Elisabeth、Opel Nils
Department of Psychiatry, Westf?lische Wilhelms-Universit?t M¨1nster, Albert-Schweitzer-Campus 1Department of Psychiatry and Psychotherapy, Philipps-Universit?t Marburg and University Hospital Marburg, UKGM||Center for Mind, Brain and Behavior (CMBB), Hans-Meerwein-Str. 6Department of Psychiatry and Psychotherapy, Philipps-Universit?t Marburg and University Hospital Marburg, UKGM||Center for Mind, Brain and Behavior (CMBB), Hans-Meerwein-Str. 6Department of Psychiatry, Westf?lische Wilhelms-Universit?t M¨1nster, Albert-Schweitzer-Campus 1Department of Psychiatry, Westf?lische Wilhelms-Universit?t M¨1nster, Albert-Schweitzer-Campus 1Department of Psychiatry, Westf?lische Wilhelms-Universit?t M¨1nster, Albert-Schweitzer-Campus 1Department of Psychiatry and Psychotherapy, Philipps-Universit?t Marburg and University Hospital Marburg, UKGM||Center for Mind, Brain and Behavior (CMBB), Hans-Meerwein-Str. 6Department of Psychiatry and Psychotherapy, Philipps-Universit?t Marburg and University Hospital Marburg, UKGM||Center for Mind, Brain and Behavior (CMBB), Hans-Meerwein-Str. 6Department of Psychiatry and Psychotherapy, Philipps-Universit?t Marburg and University Hospital Marburg, UKGM||Center for Mind, Brain and Behavior (CMBB), Hans-Meerwein-Str. 6Department of Psychiatry, Westf?lische Wilhelms-Universit?t M¨1nster, Albert-Schweitzer-Campus 1Department of Psychiatry and Psychotherapy, Philipps-Universit?t Marburg and University Hospital Marburg, UKGM||Center for Mind, Brain and Behavior (CMBB), Hans-Meerwein-Str. 6Department of Psychiatry, Westf?lische Wilhelms-Universit?t M¨1nster, Albert-Schweitzer-Campus 1Department of Psychiatry and Psychotherapy, Philipps-Universit?t Marburg and University Hospital Marburg, UKGM||Department of Psychiatry and Psychotherapy, University of BonnDepartment of Psychiatry and Psychotherapy, Philipps-Universit?t Marburg and University Hospital Marburg, UKGM||Center for Mind, Brain and Behavior (CMBB), Hans-Meerwein-Str. 6Department of Psychiatry and Psychotherapy, Philipps-Universit?t Marburg and University Hospital Marburg, UKGM||Center for Mind, Brain and Behavior (CMBB), Hans-Meerwein-Str. 6Department of Psychiatry, Westf?lische Wilhelms-Universit?t M¨1nster, Albert-Schweitzer-Campus 1Department of Psychiatry, Westf?lische Wilhelms-Universit?t M¨1nster, Albert-Schweitzer-Campus 1Department of Psychiatry, Westf?lische Wilhelms-Universit?t M¨1nster, Albert-Schweitzer-Campus 1Department of Psychiatry, Westf?lische Wilhelms-Universit?t M¨1nster, Albert-Schweitzer-Campus 1||Interdisciplinary Centre for Clinical Research, IZKF, University of M¨1nster
神经病学、精神病学医学研究方法
Covid-19mental healthstressBig Fivesocial support
Waltemate Lena,Meller Tina,Schmitt Simon,Meinert Susanne,Dohm Katharina,Dannlowski Udo,Pfarr Julia-Katharina,Nenadi? Igor,Kircher Tilo,Leehr Elisabeth J.,Stein Frederike,Thiel Katharina,Krug Axel,Ringwald Kai G.,Brosch Katharina,H¨1lsmann Carina,Lemke Hannah,Schrammen Elisabeth,Opel Nils.Which traits predict elevated distress during the Covid-19 pandemic? Results from a large, longitudinal cohort study with psychiatric patients and healthy controls[EB/OL].(2025-03-28)[2025-05-24].https://www.medrxiv.org/content/10.1101/2021.04.01.21254625.点此复制
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