非稳态负荷的评估方法及其对健康影响的研究新进展
Progress in Methods for the Assessment of Allostatic Load and Its Impact on Health
应激被认为是导致疾病的一个重要因素,持续的应激会使机体生理系统出现严重紊乱。非稳态负荷作为评估慢性应激下机体多个系统生理失调的综合指标,在健康的发生、发展中起着重要的作用。本文系统、全面地综述了非稳态负荷的相关概念、评估方法以及非稳态负荷对健康的影响,揭示非稳态负荷与健康之间存在着明显相关性。然而,国内外研究中关于非稳态负荷生物标志物的选择和算法尚无统一标准,这仍是未来的研究方向。
Stress is considered to be an important factor leading to diseases. Continuous stress can cause serious disorders in the physiological system of the body. Allostatic loadas a comprehensive index to assess the physiological disorders of multiple systems in the body under chronic stressplays an important role in the occurrence and development of health. This paper systematically and comprehensively reviews the related concepts and assessment methods of allostatic load and its impact on healthand reveals a significant correlation between allostatic load and health. Howeverthere is no standardized criteria for the selection and algorithm of biomarkers for allostatic load in domestic and foreign studieswhich is still a future research direction.
李懿茹、李玉红
10.12114/j.issn.1007-9572.2023.0362
医药卫生理论医学研究方法预防医学
应激,心理学非稳态非稳态负荷非稳态负荷指数健康生物标志物
Stress,psychologicalllostasisllostatic loadllostatic load indicesHealthBiomarkers
李懿茹,李玉红.非稳态负荷的评估方法及其对健康影响的研究新进展[EB/OL].(2023-07-24)[2025-08-18].https://chinaxiv.org/abs/202307.00703.点此复制
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