The consistent burden in published estimates of delirium occurrence in medical inpatients over four decades: a systematic review and meta-analysis study
The consistent burden in published estimates of delirium occurrence in medical inpatients over four decades: a systematic review and meta-analysis study
Abstract IntroductionDelirium is associated with a wide range of adverse patient safety outcomes. We sought to identify if trends in healthcare complexity were associated with changes in reported delirium in adult medical patients in the general hospital over the last four decades. MethodsWe used identical criteria to a previous systematic review, including studies using DSM and ICD-10 criteria for delirium diagnosis. Random effects meta-analysis pooled estimates across studies, meta-regression estimated temporal changes, funnel plots assessed publication bias. ResultsOverall delirium occurrence was 23% (95% CI 19%-26%) (33 studies). There was no change between 1980-2019, nor was case-mix (average age of sample, proportion with dementia) different. There was evidence of increasing publication bias over time. DiscussionThe incidence and prevalence of delirium in hospitals appears to be stable, though publication bias may mask true changes. Nonetheless, delirium remains a challenging and urgent priority for clinical diagnosis and care pathways.
Davis Daniel、Gibb Kate、Seeley Anna、Quinn Terry、Siddiqi Najma、Shenkin Susan、Rockwood Kenneth
MRC Unit for Lifelong Health and Ageing at UCL, Department of Population Science and Experimental Medicine||Acute Medical Unit, University College London Hospitals NHS Foundation Trust||Department of Medicine for the Elderly, University College London Hospitals NHS Foundation TrustMRC Unit for Lifelong Health and Ageing at UCL, Department of Population Science and Experimental Medicine||Acute Medical Unit, University College London Hospitals NHS Foundation TrustMRC Unit for Lifelong Health and Ageing at UCL, Department of Population Science and Experimental Medicine||Department of Medicine for the Elderly, University College London Hospitals NHS Foundation TrustInstitute of Cardiovascular and Medical Sciences, University of GlasgowDepartment of Health Sciences, University of YorkDepartment of Geriatric Medicine, University of EdinburghMRC Unit for Lifelong Health and Ageing at UCL, Department of Population Science and Experimental Medicine||Department of Medicine, Dalhousie University
医学研究方法神经病学、精神病学内科学
Deliriumepidemiologysystematic reviewmeta-analysis
Davis Daniel,Gibb Kate,Seeley Anna,Quinn Terry,Siddiqi Najma,Shenkin Susan,Rockwood Kenneth.The consistent burden in published estimates of delirium occurrence in medical inpatients over four decades: a systematic review and meta-analysis study[EB/OL].(2025-03-28)[2025-05-15].https://www.medrxiv.org/content/10.1101/19005165.点此复制
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