Neural mechanisms underlying the precision of visual working memory
Neural mechanisms underlying the precision of visual working memory
Abstract The neural mechanisms associated with the limited capacity of working memory has long been studied, but it is still unclear how the brain maintains the fidelity of representations in working memory. Here, an orientation recall task for estimating the precision of visual working memory was performed both inside and outside an fMRI scanner. Results showed that the trial-by-trial recall error (in radians) was correlated with delay period activity in the lateral occipital complex (LOC) during working memory maintenance, regardless of the memory load. Moreover, delay activity in LOC also correlated with the individual participant’s precision of working memory from a separate behavioral experiment held two weeks prior. Furthermore, a region within the prefrontal cortex, the inferior frontal junction (IFJ), exhibited greater functional connectivity with LOC when the working memory load increased. Together, our findings provide unique evidence that the LOC supports visual working memory precision, while communication between the IFJ and LOC varys with visual working memory load.
Zhao Yijie、Ku Yixuan、Kuai Shuguang、Zanto Theodore P.
The Key Lab of Brain Functional Genomics, MOE & STCSM, School of Psychology and Cognitive ScienceThe Key Lab of Brain Functional Genomics, MOE & STCSM, School of Psychology and Cognitive Science||Shanghai Key Laboratory of Magnetic Resonance, East China Normal University||NYU-ECNU Institute of Brain and Cognitive Science, NYU Shanghai and Collaborative Innovation Center for Brain ScienceThe Key Lab of Brain Functional Genomics, MOE & STCSM, School of Psychology and Cognitive Science||Shanghai Key Laboratory of Magnetic Resonance, East China Normal University||NYU-ECNU Institute of Brain and Cognitive Science, NYU Shanghai and Collaborative Innovation Center for Brain ScienceNeuroscape and the Department of Neurology, University of California San Francisco
生物科学研究方法、生物科学研究技术生物物理学
capacity limitsfunctional connectivityinferior frontal junctionlateral occipital complexworking memory precision
Zhao Yijie,Ku Yixuan,Kuai Shuguang,Zanto Theodore P..Neural mechanisms underlying the precision of visual working memory[EB/OL].(2025-03-28)[2025-07-16].https://www.biorxiv.org/content/10.1101/330118.点此复制
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