多期相病变CT特征对新冠肺炎临床疗效的预判

Objective To explore the value of CT multiphase lesion for prediction the clinical efficacy of patients with 2019-nCoV pneumonia. Methods The imaging and clinical data of 96 cases confirmed patients by RT-PCR (52/44, male/female; 10-83 years old) were retrospectively analyzed, and compared the differences in the phase distribution of multiphase CT lesions between the progressive group and the remittent group. Results The CT findings of the progressive group were mainly stage I (73/76, 96.05%) and stage II (75/76, 98.68%) lesions. In the remittent group, the proportion of stage I lesions (10/20, 50.00%) decreased, and the proportion of stage III (12/20, 60.00%) and stage IV(15/20,75.00%) lesions increased, there was an obvious difference between the two groups (p=0.000).In comparing stage IV and stage I lesions, stage I lesions showed more progression (73/83,87.95%) and stage IV lesions showed more remission (15/16, 93.75%), there was an obvious difference between the two stages (p=0.000). Conclusion The proportion of stage I and II lesions was higher in the progressive group, and the proportion of stage III and IV lesions increase in the remittent group. Stage I lesions were more likely to indicate progression, and stage IV lesions were more likely to indicate remission. Understanding the characteristics of CT multiphase lesions can provide imaging basis for early clinical efficacy prediction.