Consistency of left ventricular ejection fraction measurements in the early time course of STEMI
Consistency of left ventricular ejection fraction measurements in the early time course of STEMI
Structured Abstract BackgroundAssessment of left ventricular (LV) function and volume after ST-segment elevation myocardial infarction (STEMI) is recommended to guide clinical decision within and after hospitalization. Early after STEMI, initial LV reshaping and hypokinesia may affect analysis of LV function. A comparative evaluation of left ventricular ejection fraction (LVEF) and stroke volume (SV) by different imaging modalities to assess LV function early after STEMI has not been performed so far. MethodsLV function was assessed by LVEF and SV using serial imaging within 24h and 5 days after STEMI with cineventriculography (CVG), 2-dimensional echocardiography (2DE), 2D and 3D cardiovascular magnetic resonance (2D/3D) in 82 patients. Respective parameters were compared between modalities and to 3D gold standard CMR. Results2D analyses of LVEF using CVG and 2DE as well as 2D CMR yielded uniform results within 24h and 5 days of STEMI. SV assessment between CVG and 2DE at day 1 after STEMI was comparable, whereas values for SV were higher using 2D CMR on all occasions (p<0.01 all). This was due to higher LVEDV measurements. LVEF by 2D versus 3D CMR was comparable, 3D CMR yielded consistently higher volumetric values. This was not influenced by infarct location or infarct size. ConclusionsEarly after STEMI, 2D analysis of LVEF yielded robust results across all imaging techniques implying that CVG, 2DE, and 2D CMR can be used interchangeably in this setting. SV measurements to assess cardiac function differed substantially between imaging techniques due to higher intermodality-differences of absolute volumetric measurements.
Erkens Ralf、Wischmann Patricia、Georgieva Lilyana、Haberkorn Sebastian、Polzin Amin、Christidi Aikaterini、Roden Michael、B?nner Florian、Gastl Mareike、Jung Christian、Marjani Kian、Perings Stefan、Kelm Malte、Ipek Rojda、Nienhaus Fabian T.
Division of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine UniversityDivision of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine UniversityDivision of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine UniversityDivision of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine UniversityDivision of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine UniversityDivision of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine UniversityDivision of Endocrinology and Diabetology, Medical Faculty, Heinrich-Heine University||Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich-Heine University||German Center for Diabetes Research, Partner D¨1sseldorfDivision of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine UniversityDivision of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine UniversityDivision of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine UniversityDivision of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine UniversityDivision of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine UniversityDivision of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine University||Cardiovascular Research Institute D¨1sseldorf (CARID), Heinrich Heine University D¨1sseldorf, Medical FacultyDivision of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine UniversityDivision of Cardiology, Pulmonology and Vascular Medicine, Heinrich Heine University
临床医学内科学医学研究方法
STEMILV functioncineventriculographyechocardiographycardiovascular magnetic resonance
Erkens Ralf,Wischmann Patricia,Georgieva Lilyana,Haberkorn Sebastian,Polzin Amin,Christidi Aikaterini,Roden Michael,B?nner Florian,Gastl Mareike,Jung Christian,Marjani Kian,Perings Stefan,Kelm Malte,Ipek Rojda,Nienhaus Fabian T..Consistency of left ventricular ejection fraction measurements in the early time course of STEMI[EB/OL].(2025-03-28)[2025-08-19].https://www.medrxiv.org/content/10.1101/2023.01.13.23284539.点此复制
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