含亚胺酸酯的联烯醌前体底物的合成

Vinylidene o-quinone methide intermediate have a wide range of applications in asymmetric synthesis due to their high reactivity and multiple reaction sites; while imidates have diverse reactivity properties and are often used as important structural units for highly functionalized compounds, both of them have very important application value in organic chemistry and medicinal chemistry. In this paper, novel imidate-containing vinylidene o-quinone methide precursor compounds were designed and synthesized, which provided a basis for the application of vinylidene o-quinone methide intermediate in the construction of novel chiral skeletons.