Anti-SARS-CoV-2 Antibody Kinetics up to 6 months of follow-up: Result from a Nation-wide Population-based, Age Stratified Sero-Epidemiological Prospective Cohort Study in India
Anti-SARS-CoV-2 Antibody Kinetics up to 6 months of follow-up: Result from a Nation-wide Population-based, Age Stratified Sero-Epidemiological Prospective Cohort Study in India
Abstract Repeated serological testing tells about the change in the overall infection in a community. This study aimed to evaluate changes in antibody prevalence and kinetics in a closed cohort over six months in different sub-populations in India. The study included 10,000 participants from rural and urban areas in five states and measured SARS-CoV-2 antibodies in serum in three follow-up rounds. The overall seroprevalence increased from 73.9% in round one to 90.7% in round two and 92.9% in round three. Among seropositive rural participants in round one, 98.2% remained positive in round two, and this percentage remained stable in urban and tribal areas in round three. The results showed high antibody prevalence that increased over time and was not different based on area, age group, or sex. Vaccinated individuals had higher antibody prevalence, and nearly all participants had antibody positivity for up to six months.
Haldar Partha、Singh Arvind Kumar、Behera Bijayini、Patro Binod Kumar、Joshi Hari Shanker、Chaturvedi P K、Rath Ramashankar、Kar Sitanshu Sekhar、Kant Shashi、Meena Suneeta、Ahmad Mohammad、Medigeshi Guruprasad R、Rai Sanjay K、Mishra Baijayantimala、Sarkar Sonali、Guleria Randeep、Kishore Surekha、Hada Vivek、Mandal Suprakash、Kharya Pradeep、Majumder Tapan、Misra Puneet、Chinnakali Palanivel、Bairwa Mohan、Baidya Subrata、Dhodapkar Rahul
Centre for Community Medicine, All India Institute of Medical SciencesDepartment of Community and Family Medicine, All India Institute of Medical SciencesDepartment of Community and Family Medicine, All India Institute of Medical SciencesDepartment of Community and Family Medicine, All India Institute of Medical SciencesDepartment of Community and Family Medicine, All India Institute of Medical SciencesDepartment of Reproductive Biology, All India Institute of Medical SciencesDepartment of Community and Family Medicine, All India Institute of Medical SciencesDepartment of Community Medicine, Jawaharlal Institute of Postgraduate Medical Education and ResearchCentre for Community Medicine, All India Institute of Medical SciencesDepartment of Laboratory Medicine, All India Institute of Medical SciencesWHO Country Office, World Health OrganizationTranslational Health Science and Technology InstituteCentre for Community Medicine, All India Institute of Medical SciencesDepartment Microbiology, All India Institute of Medical SciencesDepartment of Community Medicine, Jawaharlal Institute of Postgraduate Medical Education and ResearchDirector, All India Institute of Medical SciencesDirector, All India Institute of Medical SciencesDepartment of Microbiology, All India Institute of Medical SciencesCentre for Community Medicine, All India Institute of Medical SciencesDepartment of Community and Family Medicine, All India Institute of Medical SciencesDepartment of Microbiology, Agartala Government Medical CollegeCentre for Community Medicine, All India Institute of Medical SciencesDepartment of Community Medicine, Jawaharlal Institute of Postgraduate Medical Education and ResearchCentre for Community Medicine, All India Institute of Medical SciencesDepartment of Community Medicine, Agartala Government Medical CollegeDepartment of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research
医学研究方法预防医学基础医学
SerologyAntibodySARS-CoV-2longitudinal
Haldar Partha,Singh Arvind Kumar,Behera Bijayini,Patro Binod Kumar,Joshi Hari Shanker,Chaturvedi P K,Rath Ramashankar,Kar Sitanshu Sekhar,Kant Shashi,Meena Suneeta,Ahmad Mohammad,Medigeshi Guruprasad R,Rai Sanjay K,Mishra Baijayantimala,Sarkar Sonali,Guleria Randeep,Kishore Surekha,Hada Vivek,Mandal Suprakash,Kharya Pradeep,Majumder Tapan,Misra Puneet,Chinnakali Palanivel,Bairwa Mohan,Baidya Subrata,Dhodapkar Rahul.Anti-SARS-CoV-2 Antibody Kinetics up to 6 months of follow-up: Result from a Nation-wide Population-based, Age Stratified Sero-Epidemiological Prospective Cohort Study in India[EB/OL].(2025-03-28)[2025-04-28].https://www.medrxiv.org/content/10.1101/2023.06.15.23291475.点此复制
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