血管内皮生长因子与类风湿关节炎的关系
he essential role of vascular endothelial growth factor in the progress of rheumatoid arthritis
血管内皮生长因子通过与其受体结合发挥生物学作用,促进内皮细胞有丝分裂及其增殖分化、迁移,导致血管新生,形成血管翳,在类风湿关节炎的病理过程中发挥关键的作用。对抗血管内皮生长因子及其受体,从而阻止新生血管的形成为治愈类风湿关节炎提供了新的途径。
Vascular endothelial growth factor (VEGF), which promotes the proliferation and differentiation of endothelial cells and induce the formation of new blood vascular through the combination of VEGF receptor, plays an important role in the progress of rheumatoid arthritis. In this case, the inhibition of the formation of new blood vascular by blocking the function of VEGF and its receptor might provide a new way to treat rheumatoid arthritis.
周博达、王月丹、侯超
基础医学内科学
类风湿性关节炎血管内皮生长因子受体
rheumatoid arthritis Vascular endothelial growth factor receptor
周博达,王月丹,侯超.血管内皮生长因子与类风湿关节炎的关系[EB/OL].(2006-08-09)[2025-08-06].http://www.paper.edu.cn/releasepaper/content/200608-106.点此复制
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