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Zwitterionic AIEgens: Rational Molecular Design for NIR-II Fluorescence Imaging-Guided Synergistic Phototherapy

Zwitterionic AIEgens: Rational Molecular Design for NIR-II Fluorescence Imaging-Guided Synergistic Phototherapy

来源:ChemRxiv_logoChemRxiv
英文摘要

Fluorescence imaging in the second near-infrared region (NIR-II) can penetrate tissue at centimeter depths and obtain high fidelity of images. However, facile synthesis of small-molecule fluorescent photosensitizers for efficient NIR-II fluorescence imaging as well as photodynamic and photothermal combinatorial therapies (PDT-PTT) is still a challenging task. Herein, we reported a rational design and facile synthesis protocol for a series of novel NIR-emissive zwitterionic luminogens with aggregation-induced emission (AIE) features for cancer phototheranostics.

qian wu、yi wu、Miaomiao Kang、wei zhu、Kai LI、Dong Wang、Lei Wang、Ben Zhong Tang、Zhijun Zhang、Chunbin Li

qian wuyi wuMiaomiao Kangwei zhuKai LIDong WangLei WangBen Zhong TangZhijun ZhangChunbin Li

10.26434/chemrxiv.12464120.v2

生物科学研究方法、生物科学研究技术药学肿瘤学

aggregation-induced emissionNIR-II fluorescence imagingphotodynamic therapyphotothermal therapyanticancer

qian wu,yi wu,Miaomiao Kang,wei zhu,Kai LI,Dong Wang,Lei Wang,Ben Zhong Tang,Zhijun Zhang,Chunbin Li.Zwitterionic AIEgens: Rational Molecular Design for NIR-II Fluorescence Imaging-Guided Synergistic Phototherapy[EB/OL].(2020-06-24)[2025-05-21].https://chemrxiv.org/engage/chemrxiv/article-details/60c74cfd469df478fff441ed.点此复制

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