4+CD25+调节性T细胞与人类获得性免疫缺陷病毒感染
he role of regulatory T lymphocyte in human immunodeficiency syndrome
4+CD25+调节性T细胞，是调节性T 细胞中功能最重要的一类。它是一类具有特殊免疫调节功能的T细胞亚群。它能够抑制自身免疫病的发生，参与肿瘤免疫的调节,在感染和移植免疫中也发挥着重要作用。T细胞的这一亚群具有免疫调节和免疫抑制的特性，新近发现它亦与艾滋病的发生、发展关系密切。本文就CD4+CD25+调节性T细胞与人类获得性免疫缺陷病毒（HIV）感染之间关系进行初步的探讨。
4+CD25+regulatory T cell is one of most important subsets of regulatory T cells with special function of regulation. These cells can prevent autoimmune diseases, regulate the antitumor immunity and play a crucial role in suppressing immune responses to inflammation and transplantation. This subset is hyporesponsive and anergic to antigen stimulation. Most recently, it was demonstrated that they participated in the immune deficiency in human immunodeficiency virus (HIV) infection. Here we review the knowledge and some new discoveries of the roleCD4+CD25+Treg plays in HIV infection.
徐兰 、王月丹、贺琼 、吴利洋 、邓路瑶 、杜桂书、徐赫
基础医学
HIV爱滋病调节性T细胞感染
HIVAIDSCD4+CD25+Treginfection
徐兰 ,王月丹,贺琼 ,吴利洋 ,邓路瑶 ,杜桂书,徐赫 .4+CD25+调节性T细胞与人类获得性免疫缺陷病毒感染[EB/OL].(2007-02-14)[2025-08-18].http://www.paper.edu.cn/releasepaper/content/200702-173.点此复制
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