Prevalence of heterotrophic methylmercury detoxifying bacteria across oceanic regions
Prevalence of heterotrophic methylmercury detoxifying bacteria across oceanic regions
ABSTRACT Microbial reduction of inorganic divalent mercury (Hg2+) and methylmercury (MeHg) demethylation is performed by the mer operon, specifically by merA and merB genes respectively, but little is known about the mercury tolerance capacity of marine microorganisms and its prevalence in the global ocean. Here, we explored the distribution of these genes in 290 marine heterotrophic bacteria (Alteromonas and Marinobacter spp.) isolated from different oceanographic regions and depths, and assessed their tolerance to diverse concentrations of Hg2+ and MeHg. About 25% of the isolates presented merA and only 8.9% presented both merAB genes, including the strain ISS312 that exhibited the highest tolerance capacity and a degradation efficiency of 98.2% in 24 h. Fragment recruitment analyses of ISS312 genome against microbial metagenomes indicated an extensive distribution across the global bathypelagic ocean. Our findings highlighted that mercury resistance genes are widely distributed in a non-highly polluted environment such as the pelagic marine environment, and that degradation of the neurotoxic MeHg can be performed through the ocean water column by some heterotrophic bacteria at high efficiency with important implications in the biogeochemical cycle of mercury and potentially for the environment and human health. TeaserActive mercury resistance genes detected in marine cultured bacteria are widely distributed in the ocean including the bathypelagic zone.
Capilla Miguel、S¨￠nchez Pablo、Acinas Silvia G.、Pereira Garc¨aa Carla、Bravo Andrea G.、Trujillo Laura、S¨￠nchez Olga、Pla i Ferriol Mart¨a、Rodr¨aguez Mart¨an-Doimeadios Rosa del Carmen、Sanz-S¨￠ez Isabel
Research Group in Environmental Engineering (GI2AM), Department of Chemical Engineering, University of Valencia, Av. De la Universitat S/NDepartament de Biologia Marina i Oceanografia, Institut de Ci¨¨ncies del Mar, ICM-CSICDepartament de Biologia Marina i Oceanografia, Institut de Ci¨¨ncies del Mar, ICM-CSICDepartament de Biologia Marina i Oceanografia, Institut de Ci¨¨ncies del Mar, ICM-CSICDepartament de Biologia Marina i Oceanografia, Institut de Ci¨¨ncies del Mar, ICM-CSICDepartament de Biologia Marina i Oceanografia, Institut de Ci¨¨ncies del Mar, ICM-CSICDepartament de Gen¨¨tica i Microbiologia, Facultat de Bioci¨¨ncies, Universitat Aut¨°noma de BarcelonaDepartament de Gen¨¨tica i Microbiologia, Facultat de Bioci¨¨ncies, Universitat Aut¨°noma de BarcelonaEnvironmental Sciences Institute (ICAM), Department of Analytical Chemistry and Food Technology, University of Castilla-La ManchaDepartament de Biologia Marina i Oceanografia, Institut de Ci¨¨ncies del Mar, ICM-CSIC
海洋学环境科学理论微生物学
mercurymethylmercurymarine bacteriamercury resistant bacteriamerAmerBminimum inhibitory concentration (MIC)
Capilla Miguel,S¨￠nchez Pablo,Acinas Silvia G.,Pereira Garc¨aa Carla,Bravo Andrea G.,Trujillo Laura,S¨￠nchez Olga,Pla i Ferriol Mart¨a,Rodr¨aguez Mart¨an-Doimeadios Rosa del Carmen,Sanz-S¨￠ez Isabel.Prevalence of heterotrophic methylmercury detoxifying bacteria across oceanic regions[EB/OL].(2025-03-28)[2025-04-26].https://www.biorxiv.org/content/10.1101/2021.08.09.455674.点此复制
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