|国家预印本平台
首页|融合先验知识特征的甲状腺乳头状癌中央区淋巴结转移人工智能诊断模型

融合先验知识特征的甲状腺乳头状癌中央区淋巴结转移人工智能诊断模型

rtificial Intelligence Diagnosis Model of Central Compartment Lymph Node Metastasis in Papillary Thyroid Carcinoma Fusing Prior Knowledge Features

中文摘要英文摘要

融合先验知识特征的甲状腺乳头状癌中央区淋巴结转移人工智能诊断模型:目的:基于甲状腺超声图像,利用人工智能技术,融合先验知识,构建甲状腺乳头状癌(Papillary Thyroid Carcinoma, PTC)患者中央区淋巴结转移(Central Compartment Lymph Node Metastasis, CLNM)人工智能诊断模型。 方法:采集整理2018年1月至2019年12月合作医院处符合研究标准的774例PTC患者的临床资料及超声图像,进行相应数据标注,构建本研究的全新数据集。利用深度学习中卷积神经网络、残差学习、空间池化等方法,构建PTC患者CLNM智能诊断模型,并在其中融入先验知识特征。此外对模型性能进行全面评估。 结果:在测试集中,本模型预测PTC患者CLNM的准确性、敏感性、特异性可达80.62%、90.24%、63.83%。 结论:本研究构建的人工智能诊断模型可用于诊断PTC患者CLNM,因其敏感性高尤其适用于初步筛查,同时可为临床治疗方案的决策提供依据。

Objective: To establish an artificial intelligent diagnosis model of CLNM in patients with PTC based on thyroid ultrasound images, using artificial intelligence technology and fusing prior knowledge. Methods: The clinical data and ultrasound images of 774 patients with PTC who met the research standards in the partner hospitals from January 2018 to December 2019 were collected and sorted, and the corresponding data were marked to construct a new data set for this study. Using deep learning methods such as convolutional neural network, residual learning, and spatial pooling, an intelligent diagnosis model of CLNM in patients with PTC was constructed, and prior knowledge features were incorporated into it. Besides, a comprehensive evaluation of the model performance is carried out. Results: In the test set, the accuracyArtificial Intelligence Diagnosis Model of Central Compartment Lymph Node Metastasis in Papillary Thyroid Carcinoma Fusing Prior Knowledge Features, sensitivity and specificity of this model in predicting CLNM in patients with PTC were 80.62%, 90.24% and 63.83%. Conclusion: The artificial intelligence diagnostic model constructed in this study can be used to diagnose CLNM in patients with PTC. It is especially suitable for initial screening due to its high sensitivity, and can also provide a basis for decision-making of clinical treatment plans.

张洪刚、孙文轩

肿瘤学临床医学基础医学

深度学习图像分类先验知识特征甲状腺乳头状癌中央区淋巴结转移

deep learningimage classificationprior knowledge featurespapillary thyroid carcinomacentral compartment lymph node metastasis

张洪刚,孙文轩.融合先验知识特征的甲状腺乳头状癌中央区淋巴结转移人工智能诊断模型[EB/OL].(2022-03-14)[2025-08-05].http://www.paper.edu.cn/releasepaper/content/202203-167.点此复制

评论