不对称催化硫的迈克尔反应的研究进展
Recent Advances in Organocatalytic Asymmetric Sulfa-Michael Reactions
手性含硫结构是众多天然产物和药物分子的关键骨架，广泛应用于很多重要的领域。在此背景下，构建手性含硫化合物的不对称催化反应成为近年来不对称催化化学领域的热点。本篇综述介绍了生成手性含硫化合物的一种重要的有机不对称催化反应途径--硫的迈克尔反应的研究进展，主要通过和活化烯烃直接硫的迈克尔加成反应和包含硫的迈克尔加成在内的串联反应两种合成策略实现的。
he chiral sulfur-containing compounds have many utilities in numerous important areas. In the context, the research on the asymmetric reactions to construct chiral sulfur-containing compounds is always hot area in asymmetric chemistry. This short review summarizes organocatalytic asymmetric sulfa-Michael reactions, which belong to the most important protocol to access chiral sulfur-containing compounds. Two synthetic strategies are discussed, including direct sulfa-Michael addition to various activated alkenes and sulfa-Michael-involved cascade reactions
朱博、江智勇、杨宇婷
有机化学工业制药化学工业精细化学工业
不对称催化手性含硫化合物迈克尔加成
chiral sulfur-containingasymmetric reactionssynthetic strategies
朱博,江智勇,杨宇婷.不对称催化硫的迈克尔反应的研究进展[EB/OL].(2014-01-20)[2025-08-18].http://www.paper.edu.cn/releasepaper/content/201401-894.点此复制
评论