US、HCT、MRI、EUS对胰腺癌肿瘤大小及周围组织浸润的前瞻性评估
prospective study on the assessment of primary tumor and it’s locoregional extension of pancreatic carcinoma comparing ultrasonography, helical computed tomography, magnetic resonance imaging, and endoscopic ultrasonography.
目的 前瞻性评估US、HCT、EUS 和 MRI在胰腺癌肿瘤大小测量及肿瘤周围组织浸润的预测价值及其临床意义。方法 对68例连续收治并行手术治疗的胰腺癌术前进行US、HCT、EUS 和 MRI检查,每种方法均由两位医师对其肿瘤最大径、最小径及肿瘤周围组织浸润情况进行前瞻性评估,并与手术病理结果进行对比。 结果 在四种方法中,EUS是评估肿瘤大小最准确的方法,最大径和最小径的回归系数分别为1.0250(P=0.0426) 和0.9873(P<0.0001)。在局部组织侵犯的评估中,EUS准确率最高(76%),同时具有最高敏感性(80%),而MRI具有最高阳性预测价值(97%),单元logistic回归显示没有任何一种检查方法在胰腺癌局部组织侵犯预测方面与外科发现有显著相关性(P﹥0.05)。结论 提示EUS是评估胰腺癌肿瘤大小最准确的方法,在肿瘤局部组织侵犯预测方面尚需多种方法联合应用。
Objective: To evaluate prospectively the efficacy and clinical significance of US, HCT, EUS and MRI in the assessment of primary tumor and it’s extension of pancreatic carcinoma. Methods Consecutive 68 patients with pancreatic carcinoma were studied. All of them were examined by US, HCT, EUS and MRI. Results of each imaging techniques regarding primary tumor and loco-regional extension were compared with the surgical and pathological findings. Results EUS had the highest accuracy in assessing the tumor size, the regression coefficients of the maximal and minimal diameter were 1.0250(P= 0.0426) and 0.9873(P<0.0001) respectively. In assessing locoregional extent of primary tumor, EUS had the highest accuracy (76%) and the highest sensitivity(80%), MRI had the highest positive value(97%), but none of t the four techniques was significantly correlated with the surgical findings through univariate logistic regression. Conclusions EUS is the most useful individual imaging techniques in the assessment of tumor size, more than one techniques should be used in the assessment of loco-regional extent of primary tumor.
王成锋、郝玉芝、王贵齐、陈雁、欧阳汉、田艳涛、赵平、赵心明、张红梅
肿瘤学临床医学医学研究方法
胰腺肿瘤,彩色血流多普勒,内镜超声检查,螺旋CT,核磁共振
pancreatic carcinomaUltrasonographyHelical Computed TomographyMagnetic Resonance ImagingEndoscopic Ultrasonography
王成锋,郝玉芝,王贵齐,陈雁,欧阳汉,田艳涛,赵平,赵心明,张红梅.US、HCT、MRI、EUS对胰腺癌肿瘤大小及周围组织浸润的前瞻性评估[EB/OL].(2008-04-08)[2025-08-18].http://www.paper.edu.cn/releasepaper/content/200804-218.点此复制
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