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泛素-26S蛋白酶体系统对植物病害发生及抗病性的调控功能

Roles of ubiquitin-26S proteasome system in plant disease development and resistance

中文摘要英文摘要

泛素化是一种重要的蛋白翻译后修饰方式。泛素化蛋白通常被26S蛋白酶体降解。泛素-26S蛋白酶体系统在真核生物中普遍存在,而且该体系组成因子占生物整个基因组的比例很高。泛素-蛋白酶体途径是高等植物的主要蛋白质降解途径,其作用涉及到生物体的整个生命过程,包括细胞周期控制、程序性细胞死亡,植物发育,自交不亲和性以及光、糖和激素的信号传导,因而在应对外界环境改变中起重要作用。此外,近些年越来越多研究发现,泛素-26S蛋白酶体系统还对植物病害发生、防卫反应和抗病性起重要调控作用。本文综述了植物泛素-26S蛋白酶体系统的组成、功能和作用机理,以及该系统对植物防卫反应和抗病性、植物病害发生的调控功能等方面的研究进展。

Ubiquitylation is one of the most important post-translational modification. Ubiquitylated proteins are often degraded by 26S proteasome. Ubiquitin-26S proteasome system conservatively exists in eukaryotes. Components of ubiquitin-26S proteasome system frequently account for high proportion of the whole genome. Ubiquitin-26S proteasome system is the major pathway to degrade proteins in higher plants. It is involved in the whole life processes of organisms, including cell cycle control, programmed cell death, plant development, self-incompatibility and signal transduction of light, sugar and hormones, and thus plays important roles in adaptation to environmental changes. In addition, more and more recent studies reveal that the ubiquitin-26S proteasome system is also essential to regulating plant disease development, defense responses and disease resistance. This paper reviews the progress on the composition, function and mechanisms of the ubiquitin-26S proteasome system in plant and its roles in plant defense responses and resistance as well as plant disease development.

曹嘉懿、赖亿玉、蔡新忠

分子生物学植物学生物化学

植物病理学泛素化26S蛋白酶体蛋白降解病害抗病性

Plant pathologyUbiquitylation26S proteasomeProtein degradationDiseaseResistance

曹嘉懿,赖亿玉,蔡新忠.泛素-26S蛋白酶体系统对植物病害发生及抗病性的调控功能[EB/OL].(2015-12-16)[2025-08-05].http://www.paper.edu.cn/releasepaper/content/201512-899.点此复制

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