代谢性危险因素对北京社区居民新发高血压的影响

Objective The study was conducted to explore if the new onset hypertension related with metabolic risk factors and lifestyle in Beijing community residents and to provide some suggestions for primary prevention.Method A population-based survey with a randomly cluster sampling was conducted in four communities of Beijing,including Haidian,Yuetan,Chuiyangliu and Daxing from June to August in 2007.A total of 10054 residents were included to receive a field investigation with regarding to cardiovascular risks.From June to August in 2009,7222 residents who attented the base-survey received the same investigation again.The relationship between metabolic risk factors and lifestyle with new onset hypertension were analyzed by Multivariate and logistic regression.Result 4034 subjects had normal blood pressure at baseline and 973 of them(24.1%) had developed into hypertension two years later.Multiple logistic analysis demonstrated metabolic risk factors that contributed to hypertension were prehypertension,age,high cholesterol,overweight,obesity,waist circumstance and heavy alcohol drinking, the Odds Ratios(OR) and 95% confidence interval (95%CI) of them were 3.624(3.075～4.270),1.026(1.018～1.035),1.164(1.015～1.326),1.749 (1.314～2.206),2.413(1.927～3.026),1.328 (1.211,1.455) and 1.507(1.205～1.884) respectively.The protective factors included BMI loss and graduate or above education level,the OR(95%CI) were 0.892(0.673～1.182) and 0.629(0.445～0.891)respectively.Conclusion New onset hypertension in Beijing mainly related with pre-hypertension,high cholesterol,overweight or obesity,low education level and always alcohol drinking.We should pay more attention to metabolic risk factors and lifestyle change to reduce the new onset hypertension in China.n)