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VR训练对轻度认知障碍老年人认知功能的影响及神经机制

Effects of VR training on cognitive function in older adults with mild cognitive impairment and its neural mechanisms

中文摘要英文摘要

轻度认知障碍(mild cognitive impairment, MCI)老年人是痴呆的高危人群,然而其大脑仍具有可塑性。基于虚拟现实(virtual reality, VR)技术的训练干预有助于延缓MCI向痴呆的进展。VR训练能够改善MCI老年人的整体认知功能,特别是记忆、注意和执行功能,其干预效果受到沉浸程度、训练形式和任务内容等因素的影响。VR训练提高了MCI老年人大脑神经的活动效率,表现为相关脑区激活程度的变化以及脑区间连通性的提高。VR训练有望成为MCI老年人认知改善的补充方法,未来研究应明确VR干预的量效关系,关注其长期效应,并深入探索VR训练改善MCI老年人认知功能的潜在机制。

Elderly people with mild cognitive impairment (MCI) is a high-risk group for dementia. However, their brains retain structural and functional plasticity. Virtual reality (VR) based training can help delay the progression of MCI towards dementia. VR training can improve the overall cognitive function, especially memory, attention, and executive function?of MCI elderly people.?The intervention effect is influenced by factors such as immersion level, training form, and task content. VR training improves the efficiency of neural activity in elderly MCI patients, which is manifested by changes in the activation level of relevant brain regions and an increase connectivity between brain regions. VR training is expected to become a supplementary method for cognitive improvement in elderly MCI patients. Future research should clarify the dose-effect relationship of VR intervention, focus on its long-term effects, and further explore the potential mechanisms of VR training to improve cognitive function in elderly MCI patients.

昌思琴、戴元富、蒋长好、黄辰

10.12074/202408.00246V1

神经病学、精神病学基础医学预防医学

虚拟现实轻度认知障碍老年人认知功能脑功能

virtual realitymild cognitive impairmentelderlycognitive functionbrain function

昌思琴,戴元富,蒋长好,黄辰.VR训练对轻度认知障碍老年人认知功能的影响及神经机制[EB/OL].(2024-08-27)[2025-08-03].https://chinaxiv.org/abs/202408.00246.点此复制

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